Through out the play Lady Macbeth changes. First she's the dominant partner in the relationship between herself and Macbeth. Being the siren of greater things to come, but also leading Macbeth down the path to self destruction. THe first stone acrossed this trecherous river is the death of king Duncan. After this act, the bloodshed became reactive. The next stone on the path was the cold blooded slaughter of the two previously drunk chamberlains. Then upon the next bloody stone comes the death of Macbeth's best friend, Banquo, along with his son Flaonce. An unexpected jump in the path takes place with the death of Lady Macduff and her son. Upon this stone Macbeth does stand. Not quite acrossed the river, but close. Like Macbeth, Lady Macbeth has been crossing a river of a dangerous sort. She also led herself down a path of self destruction. After every killing she becomes more and more how Macbeth was at the beginning of the play. She's becoming more caring, and doubting their actions of previous glorification. Lady Macbeth starts sleepwalking, while Macbeth suffers from Insomnia. While the Lady walks, she speaks of what has happened, each mention of the murders you have previously encounterd in this paper. A gentlewoman and a Doctor watch one of the Lady's nightly romps through the castle, speaking of the murders. "Out, damned spot, out, i say! one. two. why then, 'tis time to do 't. hell is murky. fie, my lord, fie, a soldier and afread? what need we fear who knows it, when none can call our power to account? yet who would have thought that old man to have so much blood in him?"(5. 1. 37-42)
The crime that's alluded to above is the death of Duncan. The only crime in which she had taken a great majority in. "The thane of fife had a wife. where is she now? what, will these hands ne'er be clean? no more o' that, my lord, no more o' that. you mar all with this starting"
The dialogue above is dominatly referencing the slaughter of Macduff's wife, children, and servents. Also it touches on the fact she can't clean her hands from the first murder. you can't wash blood away with blood, but that's exactly what they're trying to do. Lady Macbeth had no knowledge of this from Macbeth, but probally hear rumors of it floating around and knew right off Macbeth had done it.
"Wash your hands. put on your nightgown. look not so pale. i tell you yet again, Banquo's buried; he cannot come out on 's grave"
Very straight forward really, for most part, it's referencing the killing of Macbeths's loyal friend, and second their dinner party. Where Macbeth, possibly out of the knowledge of Banquo's not arriving due to his death, saw him in his seat at the table of guests, like he promised to be, he's be there no matter what, not even death could stop him. Again, Lady Macbeth had no idea this had happen, only by rumors did she put things together from the party.
The pattern of her remorse is as follows. She started Macbeth on this trail by having him kill Duncan, and then after that she did nothing, Macbeth was self motivated. But Lady Macbeth knowing that she had started this felt that she was guilty of the same crimes because she started this all off; the spark that set off the powder keg.